Generic Name: delavirdine
Brand Name: Rescriptor
Drug Class: HIV, NNRTIs
What is delavirdine, and what is it used for?
Delavirdine is an oral medication that is used for the treatment of infections with the human immunodeficiency virus (HIV). It is similar to efavirenz (Sustiva) and nevirapine (Viramune). Delavirdine is in a class of drugs called reverse transcriptase inhibitors which also includes zalcitabine (Hivid), zidovudine (Retrovir), didanosine (Videx), and lamivudine (Epivir).
Reverse transcriptase is the enzyme that the virus uses to form this new DNA. Delavirdine directly inhibits the activity of reverse transcriptase and blocks the production of DNA and new virus. Delavirdine does not kill existing HIV virus, and it is not a cure for HIV. Delavirdine was approved by the FDA in April 1997.
What are the side effects of delavirdine?
The most common side effects of delavirdine are:
Other important side effects include
What is the dosage for delavirdine?
The recommended dose for adults is 400 mg three times daily. To administer as a solution four 100 mg tablets in at least 3 oz of water should stand for a few minutes. It then shoud be mixed and consumed in its entirety immediately. Delavirdine may be administered without regard to meals since food does not reduce its absorption.
Pregnancy and breastfeeding
It is not known whether delavirdine is secreted in breast milk. HIV infected mothers should not nurse their infants because of the risk of transmitting HIV to an infant that is not infected.
What else should I know about delavirdine?
What preparations of delavirdine are available?
Tablets: 100 and 200 mg
How should I keep delavirdine stored?
Delavirdine should be stored at room temperature, 15 C to 30 C (59 F to 86 F).
QUESTION
What is HIV? See AnswerSummary
Delavirdine is a drug prescribed along with other anti-HIV drugs to treat HIV infection. The most common side effects of delavirdine are rash, headaches, diarrhea, nausea, vomiting and weakness. Several drugs interact with delavirdine.
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Human Immunodeficiency Virus (HIV)
HIV (human immunodeficiency virus) is a sexually transmitted virus that attacks the immune system. If it is not treated, it can lead to AIDS (acquired immunodeficiency syndrome). Currently, there is no cure for HIV. Once someone is infected, they have it for life, though with treatment, people with HIV can live long, healthy, fulfilling lives.
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Can the HIV Virus Go Away?
There is no cure or vaccine for human immunodeficiency virus (HIV) infection; however, early treatment can help increase the life expectancy of infected people.
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AIDS (Acquired Immunodeficiency Syndrome)
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Can I Get HIV From Casual Contact Like Hugging or Touching?
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Is It Possible for HIV to Go Away on Its Own?
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Can I Test HIV Positive If My Viral Load is Undetectable?
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Can HIV be Cured Naturally?
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Treatment & Diagnosis
Medications & Supplements
- Drugs: Questions to Ask Your Doctor or Pharmacist about Your Drugs
- Drug Interactions
- Retrovir (zidovudine, ZDV, formerly called AZT)
- What Are NNRTIs In Antiretroviral Therapy for HIV Infection?
- didanosine (Videx, Videx EC)
- lamivudine (3tc) (Epivir; Epivir HBV)
- stavudine (Zerit)
- efavirenz (Sustiva)
- nevirapine (Viramune, Viramune XR)
- Side Effects of Rescriptor (delavirdine)
- Combivir (lamivudine and zidovudine)
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.