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- Dosage
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**COMMENTSTAGLIST**
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**OTHERTAGLIST**
Brand Name: Lactated Ringer's Solution
Generic Name: sodium chloride, potassium chloride, sodium lactate, and calcium
Drug Class: N/A
What is Lactated Ringer's solution, and how does it work (mechanism of action)?
Sodium chloride, potassium chloride, sodium lactate, and calcium is a sterile solution for fluid and electrolyte replenishment. It restores fluid and electrolyte balances, produces diuresis, and acts as an alkalizing agent (reduces acidity). The FDA approved Ringer's solution in plastic containers in 1971.
What brand names are available for Lactated Ringer's solution?
Lactated Ringer's solution
Is Lactated Ringer's solution available as a generic drug?
Yes
Do I need a prescription for Lactated Ringer's solution?
Yes
What is the dosage for Lactated Ringer's solution?
Adult dosing of Lactated Ringer's solution is as directed by the physician. Dosing is individualized based on the patient's age, weight, ongoing treatment, and clinical condition.
Safe and effective use of Lactated Ringer's solution in children is based on clinical practice.
What are the side effects of Lactated Ringer's solution?
Side effects of Lactated Ringer's solution are:
- chest pain,
- abnormal heart rate,
- decreased blood pressure,
- troubled breathing,
- cough,
- sneezing,
- rash,
- itching, and
- headache.
Which drugs or supplements interact with Lactated Ringer's solution?
Lactated Ringer's solution should not be mixed with ceftriaxone (Rocephin) due to the significant risk of ceftriaxone and calcium precipitation.
Is Lactated Ringer's solution safe to take if I'm pregnant or breastfeeding?
There are no adequate studies done on Lactated Ringer's solution to determine safe and effective use in pregnant women.
Use by women who are breastfeeding mothers has not been adequately evaluated.
What else should I know about Lactated Ringer's solution?
Lactated Ringer's solution is available in 250 ml, 500 ml, and 1000 ml in specific plastic containers.
- Lactated Ringer's is composed of sodium chloride 6 g/L, sodium lactate 3.1 g/L, potassium chloride 0.3 g/L, and calcium chloride 0.2 g/L.
- Lactated Ringer's contains ions of sodium 130 mEq/L, potassium 4 mEq/L, calcium 2.7 mEq/L, chloride 109 mEq/L, and lactate 28 mEq/L.
- Lactated Ringer's has an osmolarity of 273 mOsmol/L, pH of 6.5, and caloric content of 9 kcal/L.
Store Lactated Ringer's solution at room temperature of 25 C, avoiding excessive heat. Brief exposure to up to 40 C does not affect the product.
SLIDESHOW
See SlideshowSummary
Sodium chloride, potassium chloride, sodium lactate and calcium (Lactated Ringer's solution) is a sterile solution used to replace fluids and electrolytes in patients with unbalanced blood fluid, and it also is used for an alkalizing agent. Review side effects, drug interactions, dosage, storage, and pregnancy safety information prior to using this medication.
Related Disease Conditions
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Heat Rash
Heat rash is a skin irritation caused by excessive sweating. It can occur at any age and it appears as a rash that itches or feels prickly and looks like a red cluster of pimples or small blisters. Heat rash remedies include OTC creams and sprays. Usually heat rash resolves when the skin is cooled sufficiently. Medical treatment may be necessary if the sweat glands become infected.
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Diarrhea
Diarrhea is a change in the frequency and looseness of bowel movements. Symptoms associated with diarrhea are cramping, abdominal pain, and the sensation of rectal urgency. Causes of diarrhea include viral, bacterial, or parasite infection, gastroenteritis, food poisoning, and drugs. Absorbents and anti-motility medications are used to treat diarrhea.
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Dehydration in Adults & Children
Dehydration is the excessive loss of body water. There are a number of causes of dehydration including heat exposure, prolonged vigorous exercise, and some diseases of the gastrointestinal tract. Symptoms of dehydration include headache, lightheadedness, constipation, and bad breath. Treatment for dehydration is to replace lost fluids and electrolytes.
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Heat Stroke
Heat stroke (heatstroke or sun stroke) is a form of hyperthermia. Heat stroke is a true medical emergency that can be fatal if not promptly and properly treated. Symptoms of heat stroke include high body temperature, absence of sweating, hot red or flushed dry skin, rapid pulse, difficulty breathing, strange behavior, hallucinations, confusion, agitation, disorientation, seizure, and coma. A victim of heat stroke must receive immediate treatment to avoid permanent organ damage.
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Traveler's Diarrhea
Traveler's diarrhea is generally contracted by eating contaminated food or drinking contaminated water. Food is the primary source of traveler's diarrhea. Enterotoxigenic E. coli is the cause of up to 70% of all cases of traveler's diarrhea. Five unique classes of E. coli cause gastroenteritis. Other bacteria responsible for traveler's diarrhea include Campylobacter, jejuni, shigella, and salmonella. Viruses, such as rotavirus and Norwalk virus (norovirus), and giardia lamblia, a parasite, may cause traveler's diarrhea. Prevention is careful eating and drinking of water.
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Heat Exhaustion
Heat exhaustion is a milder form of heat-related illness that can develop after several days of exposure to high temperatures and inadequate or unbalanced replacement fluids. Heat exhaustion can progress to heat stroke (a medical emergency) if not treated.
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Hyperthermia (Heat-Related Illness)
Heat-related illness include heat rash, cramps, exhaustion, stroke, and sunburn. Treatment of heat related illnesses depend on the condition, but symptoms may include headache, nausea, vomiting, dizziness, fainting, seizures, and coma. Heat stroke is a medical emergency, and may result in death if not treated promptly. Heat exhaustion may lead to heat stroke if not treated properly.
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Heat Cramps
Heat cramps usually affect people who sweat a lot during strenuous activity or work in a hot, humid environment. Symptoms of heat cramps are muscle pains or spasms, usually in the abdomen, arms or legs that occur in association with strenuous activity. Heat cramps are part of a group of heat-related illnesses. Heat cramps can sometimes lead to heat exhaustion or, in severe instances, heat stroke, which is a true medical emergency.
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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.